Glioblastoma Multiforme (GBM)

Glioblastoma multiforme (GBM) is the most common primary brain tumor.  It is also the most malignant astrocytoma.  The incidence of GBM is 2-3 cases per 100,000.  The tumor causes mass effect and invades adjacent brain tissue resulting in loss of function and neurologic decline.  Without treatment, patient’s succumb to this disease within weeks.

Diagnosis for GBM

CT and MRI scanning can be used to diagnosed GBM.  GBM tends to have typical characteristic findings on imaging studies that lead to high clinical suspicion of the diagnosis.  Stereotactic brain biopsy may be performed for definitive diagnosis.  In many cases however, open brain surgery is required urgently to avoid acute neurologic decline.  Tissue biopsy is performed in these cases during surgical decompression.

Treatment for GBM

Treatment for GBM involves a combination of surgery, radiation therapy, and chemotherapy.  Unfortunately, complete resection of the tumor does not result in cure.  Combination therapy is guided by the size of the tumor and its location.  Stereotactic radiosurgery has also been used successfully during times of recurrence.  New treatment options and strategies offer hope for improved outcomes.

At Princeton Neurological Surgery, Dr. Lipani is a board certified fellowship trained neurosurgeon in New Jersey and specialist in the treatment for GBM. Dr. Lipani treats patients from around the world as well as locally from Princeton, New Brunswick, Hopewell, Pennington and communities throughout Somerset, Middlesex, Ocean, Burlington, Monmouth and Mercer Counties for glioblastoma multiform. Dr. Lipani offers image guided brain surgery approaches and the latest in noninvasive radiosurgery procedures for GBM treatment, tailored to the needs of each patient. For the very best in GBM treatment, or to learn about CyberKnife radiosurgery, call or email us to schedule a consultation at our offices in Hamilton, New Jersey or Bridgewater, New Jersey!

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